In 1980, Araki received the runner-up prize at the 20th Tezuka Award for his debut work Poker Under Arms, which was published in Weekly Shonen Jump. In 1986, he started the series JoJo’s Bizarre Adventure in the same magazine. In Japan, cumulative circulation of the series has surpassed 120 million copies. As of 2025, he is currently serializing *The JOJOLands *in the monthly magazine Ultra Jump.
In 2009, he participated in an exhibition at the Louvre Museum, where Rohan Kishibe Goes to the Louvre (Rohan au Louvre) was unveiled. In 2013, collaborative works he created with Gucci were showcased worldwide in the fashion brand’s directly operated stores. In 2018, the Hirohiko Araki JoJo Exhibition: Ripples of Adventure was held in the National Art Center, Tokyo. This was the first time that a solo exhibition of an active manga artist has been held at a national art museum.